KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
24.24
Human Site:
S141
Identified Species:
41.03
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
S141
E
K
Q
Q
T
L
S
S
A
F
A
D
S
L
C
Chimpanzee
Pan troglodytes
XP_511585
968
108684
F138
E
T
L
R
Y
L
T
F
M
S
G
E
V
G
R
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
S234
E
K
Q
Q
T
L
S
S
A
F
A
D
S
L
C
Dog
Lupus familis
XP_853409
975
109686
S141
E
K
Q
Q
T
L
S
S
A
F
A
D
S
L
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
S143
E
K
Q
Q
T
L
S
S
A
F
A
D
S
L
C
Rat
Rattus norvegicus
XP_573211
965
109012
T141
A
D
S
L
C
P
S
T
S
L
L
Y
L
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
R139
T
M
F
D
T
K
S
R
E
L
R
W
N
A
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
T146
E
K
Q
T
T
L
S
T
E
S
S
E
G
L
C
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
S139
T
S
L
S
T
S
S
S
D
S
I
C
P
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
Y140
R
S
S
D
G
I
L
Y
S
G
K
K
S
D
T
Honey Bee
Apis mellifera
XP_392044
968
110555
G139
S
P
C
R
S
S
D
G
I
L
Y
T
G
R
K
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
S153
V
E
T
L
S
S
A
S
A
D
R
I
C
P
A
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
T163
H
K
K
Q
T
L
T
T
E
S
S
Q
S
S
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
H141
A
V
D
R
R
N
G
H
I
I
W
S
I
E
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
13.3
100
100
N.A.
100
6.6
N.A.
13.3
N.A.
53.3
20
N.A.
6.6
0
13.3
40
P-Site Similarity:
100
33.3
100
100
N.A.
100
20
N.A.
20
N.A.
73.3
20
N.A.
20
13.3
33.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
0
8
0
36
0
29
0
0
8
15
% A
% Cys:
0
0
8
0
8
0
0
0
0
0
0
8
8
0
43
% C
% Asp:
0
8
8
15
0
0
8
0
8
8
0
29
0
8
0
% D
% Glu:
43
8
0
0
0
0
0
0
22
0
0
15
0
8
0
% E
% Phe:
0
0
8
0
0
0
0
8
0
29
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
8
8
0
8
8
0
15
15
0
% G
% His:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
15
8
8
8
8
0
0
% I
% Lys:
0
43
8
0
0
8
0
0
0
0
8
8
0
0
8
% K
% Leu:
0
0
15
15
0
50
8
0
0
22
8
0
8
36
0
% L
% Met:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
8
0
0
0
8
0
0
0
0
0
0
8
8
8
% P
% Gln:
0
0
36
36
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
8
0
0
22
8
0
0
8
0
0
15
0
0
8
15
% R
% Ser:
8
15
15
8
15
22
58
43
15
29
15
8
43
15
0
% S
% Thr:
15
8
8
8
58
0
15
22
0
0
0
8
0
0
15
% T
% Val:
8
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
8
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _